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Moreover, in a double-blind PLA-controlled study, 3 weeks with intramuscular injections of 200’300 mg/week testosterone enanthate, combined with heavy strength training, was sufficient to increase maximal strength and 10-s cycle sprint performance significantly in healthy, young men (Rogerson et al. In the current study, a significant 3-fold elevation in mean serum testosterone concentration was observed from pre-administration to post-administration in the TE group, while it remained similar in the PLA control group. This indicates that the applied administration regime indeed elevated serum testosterone to levels outside the normal physiological range. Accordingly, serum oestradiol concentration was significantly elevated only in the TE group following administration (Figure 3), likely due to peripheral conversation of injected testosterone by aromatization (Matsumine et al, .

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